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纸质出版日期:2006
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宁康健1, 何胜利2, 吕锦芳1, 等. 乳核内消液提取工艺的优化研究[J]. 中国实验方剂学杂志, 2006,12(1):3-4.
NING Kang-jian1, HE Sheng-li2, L Jin-fang1, et al. The Research on Improving Production Technology of RHNXY[J]. Chinese journal of experimental traditional medical formulae, 2006, 12(1): 3-4.
目的:研究乳核内消液(RHNXY)的提取工艺并进行质量检查
以优化其提取工艺。方法:采用正交实验方法对乳核内消液处方中四味药材的挥发油提取工艺、药渣及药液与浙贝母等八味药材的水提取工艺进行优化
为指导生产提供依据。结果:(1)挥发油提取以饮片加4倍量水
浸泡1h
提取4h为最佳工艺。(2)水提取以煎煮二次
第一次加水至原药材的8倍量
第二次加原药材8倍量的水
每次煎煮1.5h
并以离心分离为最佳工艺。结论:乳核内消液的生产工艺优化研究能够降低成本
提高产品质量。
Objective:To research production technology of RHNXY and go on with quality detection of RHNXY
in order to optimize its production technology.Methods: By orthogonal design
the extraction technology with volatile oil of four crude drugs in RHNXY
and the extraction technology with water of gruffs and of eight crude drugs(including fritillariae thunbergii and so on) in RHNXY were optimized in the experiment
in order to be applied to practice.Results:(1) The extraction technology with volatile oil
which with decoction pieces added water in four times
soaked an hour
and extracted four hours
was the best one.(2) The extraction technology with water
which boiled twice and added water to eight quantities of original crude drugs at the first time and added water in eight times at the second time
lasting one and half hours every time
and separated with centrifugal
was the best one.Conclusions: Decreasing production cost and increasing quality of crude drugs were attained by optimigation production technology of RHNXY.
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