Objective:To investigate the functions of YangGanLiDan Granule(YGLDG) on anti-inflammation

pain relief and spasmolysis.Methods:The models of mouse ear tumefaction caused by xylene and rat foot tumefaction caused by carrageenan were used to observe the anti-inflammatory action of YGLDG via oral adiminstration.The effect of YGLDG on relieving pain was tested by counting body twisting induced by glacial acetic acid and measuring the latent period of licking hind foot with the hot plate method in mice.The effect on spasmolysis was studied by using isolated gallbladder of guinea pig.Results:The drug could restrain mouse ear tumefaction and rat foot tumefaction

reduce mouse body twisting numter in glacial acetic acid model and elevate the pain threshold with hot plate method

relax the spasticity of isolated gallbladder of guinea pig caused by Ach.Conclusion:The results show that YGLDG has the effects on anti-inflammation

pain relief and relaxtion of spasticity.