To examine the impact of Jianpihuashisanyu Fang and Xuezhikang recipe on the serum lipids and liver function in patients with chronic hepatitis B (CHB) and fatty liver.Method:107 patients with chronic hepatitis B and fatty liver were treated for 8 weeks and randomly divided into two groups:the research group has 62 patients treated by Jianpihuashisanyu Fang and Xuezhikang recipes (bid);the control group has 45 patients treated by Xuezhikang recipes(bid).The serial indices of serum lipids(including TC、TG、HDL-C、LDL-C、ApoA1、ApoB、LP(a))

and the liver function (including ALT、AST、CHE)were tested.Results The level of TC、LDL-C and ApoB were samely decreased in two groups(P>0.05)

but the level of TC in research group was significantly lower than that of the control(P<0.05)

the level of HCL-C and Apo A1 in research group was significantly higher than that of the control (P<0.05).In research group

the ALT、AST and CHE were significantly decreased to the normal level(P<0.01).Conclusion:Effect of the treatment of Jianpihuashisanyu Fang and Xuezhikang recipe on CHB with fatty liver is significantly better than treated by Xuezhikang recipe only.