Objective:To observe the effect of scutellarin on hemorheology of rat thrombus model induced by Carrageenan after intravenous administration of scutellarin.Method:The thrombus model was induced by a single sc dose of 1% carrageenan(5 mg·kg-1).The blood sample was collected by the puncture of the abdomen aorta and the effect of scutellarin on hemorheological parameters was observed.Result:Scutellarin inhibited significantly platelet aggregation

depressed the whole blood viscosity and influenced slightly the plasma viscosity

which indicated certain trends with extended action duration

but it did not affect the level of the hematocrit and the fibrinogen.Conclusion:The effect of scutellarin on hemorheological parameters of rat thrombus model induced by Carrageenan was due to interaction of scutellarin and its metabolites.