YANG Tong-guang1, XU Xin-mei2. Experimental Progresses in Suppressive Effects of Non-steroidal Anti-inflammatories in Chinese Materia Medica on Gastric Mucosal Damage[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 62-65.
YANG Tong-guang1, XU Xin-mei2. Experimental Progresses in Suppressive Effects of Non-steroidal Anti-inflammatories in Chinese Materia Medica on Gastric Mucosal Damage[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 62-65.DOI:
To summarize the recent experimental studies on the protection of the traditional Chinese for treating the damage of gastric mucosa with Non-steroidal anti-inflammatory drugs:The mechanism includes promoting the prostaglandin synthesis of gastric mucosa
suppressing the damage of free radical
reinforcing the gastric mucus-bicarbonate barrier
ameliorating the gastric mucosal epithelia function
ameliorating gastric mucosal blood flow and microcirculation
inhibiting gastric acid and pepsin.Most of the traditional Chinese materia medica are YI QI JIAN PI
others are HUO XUE HUA YU、QING RE JIE DU and ZI YIN SHENG JIN.More research is needed to clarify the relevance of protection of gastric mucosa and regulation of cyclooxygenase.