PENG Li-hua, LIU Shu-zhi, GUO Chun-yan, et al. Skin Penetration Property of Drugs in Two Cataplasma Carriers[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(5): 1-3.
PENG Li-hua, LIU Shu-zhi, GUO Chun-yan, et al. Skin Penetration Property of Drugs in Two Cataplasma Carriers[J]. Chinese journal of experimental traditional medical formulae, 2005, 11(5): 1-3.DOI:
Objectives:To compare the releasing rates in vitro of evodiamine and rutaecarpine in two kinds of cataplasma carriers.Methods:The releasing of evodiamine and rutaecarpine from the cataplasma carriers in vitro were measured
imitating the method of percutaneous absorption by using improved Franz'S diffusion cell and HPLC.Results:The releasing rates of Evodiamine and rutaecarpine in the carrier made of acryl ic resin copotymer and natural copolymers are higher than those in the carrier made of acrylic resin coDolymer and compounded copolymers.And both the releasing processes fit to the Higuchi equation.Conclusion:Both the cataplasma carriers have good drug releasing properties.