WEI Chang-xiu, LI Qing-ming, FU Yu-ru. Protective Effect of Naohuandan on the Impairment of Cortial and Hippocampal Neuron Induced by Beta-amy Oid Protein[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 18-20.
WEI Chang-xiu, LI Qing-ming, FU Yu-ru. Protective Effect of Naohuandan on the Impairment of Cortial and Hippocampal Neuron Induced by Beta-amy Oid Protein[J]. Chinese journal of experimental traditional medical formulae, 2004, 10(3): 18-20.DOI:
Using thiazolyl blue colorimetry(MTT) and NSE immunohistochemistry staining to observe the effect of Naohuandan on the impairment induced by beta-amyloid protein(A β)of primary cultured cortial and hippocampal neurons
we found that when treated with A β
some neurons dead
As compared with those、with non-drug containing serum
Naohuandan containing serum treament could promote the survival
the growth and the development of neurons.The results indicated that Naohuandan could reduce the neurotoxin of A β to cortial and hippocampal neurons.