Comparision of Xuanfa Moyuan Preparation and Common Threewinnut Root Treating CIA Rat[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(4): 21-23.
Comparision of Xuanfa Moyuan Preparation and Common Threewinnut Root Treating CIA Rat[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(4): 21-23.DOI:
To probe the mechanism of Xuanfa Moyuan preparation treating rats collagen-Ⅱinuced arthritis(CIA)which is similar to human RA
rats were immunized with the complex of collagen-Ⅱand complete Frund’s adjuvant.Theimmunological and morphological changes in the ratswere observed after the ratswere treatedwith XuanfaMoyuan prepa-ration common threewingnut root
damages of CIA rats joints were relieved
TNF-α and anti-CII antibody in the serumshowed some decrease.But IFN-γ showed some increase.XuanfaMoyuan prepartion could relieve the damages of CIArat’ s joints and regulate the immunology activity of CIA rats.And Xuanfa moytan preparation could produces effect morequickly than common threewingnut root.