BAI Hai-bo, WANG JIan-fei, SONG Zi-rong. Study on Optimizing the Extraction Process of Ferulic Acid and Ligustilide in Ligusticum Chuanxion Hort.[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(4): 8-10.
BAI Hai-bo, WANG JIan-fei, SONG Zi-rong. Study on Optimizing the Extraction Process of Ferulic Acid and Ligustilide in Ligusticum Chuanxion Hort.[J]. Chinese journal of experimental traditional medical formulae, 2003, 9(4): 8-10.DOI:
Objective:To optimize the extraction process of Ferulic Acid and Ligustilide in Ligusticum chuanxiong Hort.Method:The optimum extraction was investigated by the orthogonal design
Ferulic Acid and Ligustilide determined by HPLC
the concentration of ethanol
amount of ethanol
extraction time and extraction times were the four factors in the experiment.Results:The optimum extraction process was adding 10 times amount of 80% alcohol
refluxing and extraction for 3 times
1h each time.Conclution:This extraction process shows higher yield of Ferulic acid and ligustilide and is available for industrial production.