XU Shu-ling, GUAN Chong-fen, WANG Hui, et al. Experimental Study of Immune Function on Monkey of SIV Infection with Zhong Yan-Ⅰand Zhong Yan-Ⅱ[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(6): 32-34.
XU Shu-ling, GUAN Chong-fen, WANG Hui, et al. Experimental Study of Immune Function on Monkey of SIV Infection with Zhong Yan-Ⅰand Zhong Yan-Ⅱ[J]. Chinese journal of experimental traditional medical formulae, 2001, 7(6): 32-34.DOI:
In order to research the effect of ZY-Ⅰ and ZY-Ⅱ on simian immunodeficiency virus (SIV mac and SIV mac251)
we used SAIDS model to observe the influence of T and B cell proliferation induced by mitogens before and after treatment with ZY-Ⅰ. Using monoclonal antibody to label on CD4+ T cells in PBMC with indirect immunofluorescence
the percentage was analyzed by flow cytometry. Serum β2 microglobin (β2MG) was measured by ELISA in ZY-Ⅱ group. Results indicate that ZY-Ⅰ enhanced the proliferation of T and B cells induced by mitogen