FENG Liang-yuan, YAN Shun-qin, WU Shu-qin, et al. Experimental Study on the Analgesia Mechanism of Paeornia and Glycyrrhiza Dicoction[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(1): 23-25.
FENG Liang-yuan, YAN Shun-qin, WU Shu-qin, et al. Experimental Study on the Analgesia Mechanism of Paeornia and Glycyrrhiza Dicoction[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(1): 23-25.DOI:
The analgesia action was investigated in the pain model caused by formalin
and the content of NO
PGE2 and SOD of serum and spinal cord of mice with pain model caused by glacialaceticacid were also detected to study analgesia mechanism of Paeonia and Glycyrrhiza Decoction(PGD).The results indicate:(1)In Formalin pain experiment
PGD could restrain peripheral nerve twig action
and inhibit subesequent inflammatory reaction to ease pain in Ⅰ and Ⅱ phase reaction;(2)PGD could decrease the content of NO and PGE2 of serum and spinal cord of the mice and distinctly enhance the activity of SOD.