WANG Qin-mao1, LI Li1, ZHAO Yong2, et al. Effects of Qing Hua Capsule on Yong Excessive Hypertension Rats Induced by Three Factors[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(3): 14-17.
WANG Qin-mao1, LI Li1, ZHAO Yong2, et al. Effects of Qing Hua Capsule on Yong Excessive Hypertension Rats Induced by Three Factors[J]. Chinese journal of experimental traditional medical formulae, 2002, 8(3): 14-17.DOI:
Yang excessive hypertension model of rat was induced by the mixture of three traditional Chinese medicines
ephedrine and normal saline water
respectively. Results showed Qing Hua Capsule could significantly decrease blood pressure of model rats. At the same time
it could also decrease levels of SAP
DAP
LVSP
+dp/dtmax
cAMP
Ang Ⅱ and TXB2 in blood plasma. It led to the rise of 6-k-PGF1α/TXB2 ratio. In addition
the content of TMN and NE in urine was decreased. It had no effects on coagulative and fibrinolytic system. It didn't significantly change the pathology of heart and kidney.