虎金丸对CCl所致实验性肝损伤的保护作用

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- 虎金丸对CCl所致实验性肝损伤的保护作用
- Protective Effect of Hujin Pills on CCl-induced Experimental Liver Injury
- 中国实验方剂学杂志 1999年5卷第2期页码：21-23
- 作者机构：
- 作者简介：
- 基金信息：
  
  国家中医药管理局资助课题 No97A06
- DOI：
  中图分类号：
- 纸质出版日期：1999
- 稿件说明：
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黄兆胜, 黎俏梅, 王宗伟, 等. 虎金丸对CCl所致实验性肝损伤的保护作用[J]. 中国实验方剂学杂志, 1999,5(2):21-23.

Huang Zhaosheng, Li Qiaomei, Wang Zongwei, et al. Protective Effect of Hujin Pills on CCl-induced Experimental Liver Injury[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(2): 21-23.
黄兆胜, 黎俏梅, 王宗伟, 等. 虎金丸对CCl所致实验性肝损伤的保护作用[J]. 中国实验方剂学杂志, 1999,5(2):21-23. DOI：

Huang Zhaosheng, Li Qiaomei, Wang Zongwei, et al. Protective Effect of Hujin Pills on CCl-induced Experimental Liver Injury[J]. Chinese journal of experimental traditional medical formulae, 1999, 5(2): 21-23. DOI：

虎金丸ig小鼠

能显著降低CCl4所致血中ALT?AST?GST和肝中MDA水平的升高;虎金丸ig大鼠制得药物血清后

以10%浓度加入原代培养大鼠肝细胞培养液中

能显著降低10mmol/L CCl4所致培养液中ALT和MDA的升高

并使细胞存活率由55.90%提高至82.45%?

After the mice were dosed with Hujin Pill for 6 days

the raised level of ALT

AST

GST in serum and MDA in liver caused by CCl4 was ameliorated evidently.In addition

for primay cultured rat hepatocytes

rat serum containing Hujin Pills could remarkably decrease the raised level of ALT and MDA in the culture caused by 10 mmol/L CCl4

and the cell viability was improved from 55.90% to 82.45%.

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