HAN Li-wei, REN Tian-chi. Studies on the Extraction Process of Rhizoma Coptidis in Jiangtang Capsule by Orthogonal Design Method[J]. Chinese journal of experimental traditional medical formulae, 2000, 6(1): 12-14.
HAN Li-wei, REN Tian-chi. Studies on the Extraction Process of Rhizoma Coptidis in Jiangtang Capsule by Orthogonal Design Method[J]. Chinese journal of experimental traditional medical formulae, 2000, 6(1): 12-14.DOI:
the optimum extraction conditions of rhizoma coptidis in Jiangtang capsule were established.The mobile phase of HPLC was KH2PO4-Na2S2O3-H2O-CH3CN(3.4g∶1.7g∶140ml∶60ml).The best extraction process was as follows:reflux with 80% alcohol for three times
for the first time:6 times alcohol of crude drug for 2hr;the second:5times for 1.5hr and the last:4 times for 1.5hr.