Objective: To observe the effects of Buyang Huanwu decoction(BYHWD) and Xinglou Chengqi decoction(XLCQD) on the nerves functional rehabilitation and its protective effect on aminotransferase

creatinine(Cr) and blood urea nitrogen(BUN) were evaluated for Liver and kidney function in rats with cerebral ischemia. Method: Rats were divided randomly into sham

model

nimodipine

BYHWD and XLCQD groups. Rat focal cerebral ischemia model was established by middle cerebral artery occlusion (MCAO) with nylon thread.Rats were administrated with corresponding drugs by gavage before establishing model. After operation of cerebral ischemia

rats were given the corresponding drugs once a day for 14 days.Rats neurological score (NS) was evaluated and blood was taken out at 14 d and 28 d after operation

and then the rat's liver and kidney function were determined. Result: In each model group

rats NS decreased

aspartate aminotransferase(AST)

alanine aminotransferase(ALT)

Cr

BUN increased. In comparison with that of rats in each model group

NS of rats in each treatment group raised

and AST

ALT

Cr

BUN reduced obviously except 14 d in BYHWD group. In comparison with that in nimodipine and XLCQD group

the NS increased in 28 d BYHWD group

Cr in 28 d BYHWD group reduced Significantly. NS of rats obviously ascended in each treatment group and AST

ALT decreased in 28 d BYHWD group. Conclusion: After cerebral ischemia the neurological function of rats restorated slowly. It is indicated that the treatment of XLCQD and BYHWD can Promote the recovery of neurological function injuried by cerebral ischemia and BYHWD has the more significant roles in the recovery of neurological function. Cerebral ischemia can lead to liver and kidney function damage

BYHWD and XLCQD play a different role in different time after cerebral ischemia

and the role of BYHWD is more comprehensive and significant.