Objective: To investigate the effect of triple therapy of Chinese medicine for acute cerebral infarction and its influence on cerebral blood flow. Method: Two hundred and eighty-six patients with acute cerebral infarction were randomly divided into two groups. The observation group was accepted triple therapy of Chinese medicine

including Zhongfeng Fang 1 dose daily; Zhichang Dizhu Zhongfeng Fang 1 dose daily and ginkgo leaf injection 10 mL daily. The control group was treated with ginkgo leaf injection 10 mL daily

citicoline 0.5 g iv daily. All treatment lasted for 14 days. Recovery of neurological function and the changes of cerebral blood flow were evaluated and analyzed. Result: Compared with the control group

the total efficiency of the observation group was significantly higher (88.8% vs. 74.1%

P<0.05). The mean cerebral blood flow comparison of two groups after therapy showed statistically difference [(663.5±99.3) mL·min-1 vs (615.47±96.5) mL·min-1

P<0.05]. Conclusion: Triple therapy of Chinese medicine for acute cerebral infarction results in better cerebral blood flow recovery

and helps to improve the recovery of neurological function

which worthy of further clinical application.