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纸质出版日期:2013
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周峰. 氟比洛芬酯与舒芬太尼联合用于肠道肿瘤术后的代谢调理作用分析[J]. 中国实验方剂学杂志, 2013,19(8):326-328.
ZHOU Feng. Analysis Flurbiprofen Ester and Sufentanil Joint for Intestinal Tumor Postoperative Metabolic Toning Effect[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 326-328.
周峰. 氟比洛芬酯与舒芬太尼联合用于肠道肿瘤术后的代谢调理作用分析[J]. 中国实验方剂学杂志, 2013,19(8):326-328. DOI: 10.11653/syfj2013080326.
ZHOU Feng. Analysis Flurbiprofen Ester and Sufentanil Joint for Intestinal Tumor Postoperative Metabolic Toning Effect[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(8): 326-328. DOI: 10.11653/syfj2013080326.
目的: 对比分析氟比洛芬酯联合舒芬太尼与单独使用舒芬太尼
在对肠道手术后病人所产生的镇痛作用的效果以及代谢调理作用。 方法: 将2011年2月-2012年7月接受过肠道肿瘤根治手术的80位病人作为实验调查的样本
随机分成舒芬太尼镇痛组(A组
n=40)和氟比涪芬酯联合舒芬太尼镇痛组(B组
n=40)。A
B组的病人在接受手术后的3 d内不得进食
只能通过肘静脉注射进行营养补充。在此时间内定时记录A
B组的病人在禁食阶段中的肿瘤坏死因子-α(TNF-α)、体温数值、皮质醇、氮平衡状况、镇痛的整体效果、白细胞介素-6(IL-6)以及肾上腺索的变化情况。 结果: 术后两组镇痛评分差异无统计学意义
在第3天A
B组的患者相比
第1天的镇痛效果均出现了明显的好转。术后体温、负氮平衡、TNF-α及IL-6变化B组均较A组明显(P<0.05)
但是肾上腺素的数值与皮质醇数值并没有出现明显变化。 结论: 相比单一的使用舒芬太尼进行术后镇痛
舒芬太尼和氟比洛芬酯混合镇痛的效果并没有明显的优势
但是舒芬太尼和氟比洛芬酯混合能够起到良好的术后调理效果。
Objective: To comparative analysis flurbiprofen ester joint sufentanil
and used alone sufentanil
in the patients after intestinal surgery produced by the analgesic effect and metabolic toning effect. Method: Will be in february 2011-July 2012 received intestinal cancer radical operation of 80 patients as experimental investigation of the sample
random divided into sufentanil analgesic group (group A
n=40) and fluorine than flurbiprofen ester joint sufentanil analgesic group (group B
n=40). Due to A
B group of patients after surgery after 3 days shall not eat
can only through the week intravenous nutrition supplement. In this time logging A
B group of patients in the stage of fast the tumor necrosis factor-α(TNF-α)
body temperature numerical
cortisol
nitrogen balance
the integral effect of analgesia
interleukin-6(IL-6) and adrenal line changes. Result: The two groups of analgesic score difference was statistically significant. In the third day A
B group compared with patients who the analgesic effect of 1 day all appeared obviously improved. Postoperative body temperature
negative nitrogen balance
TNF-α and IL-6 change group B than a group obviously. But adrenaline numerical and cortex leaven numerical and no apparent change. Conclusion: Compared with the use of a single sufentanil on postoperative analgesia
sufentanil and flurbiprofen ester mixed analgesic effect and no obvious advantages
but sufentanil and flurbiprofen ester mixture can play a good postoperative conditioning effect.
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