Objective: To optimize microwave extraction technology of polysaccharides from seeds of Vicia villosa

and preliminarily investigate its antioxidant activity. Method: With extraction amount of polysaccharides as index

L9(34) orthogonal test was adopted to optimize extraction technology of polysaccharides from seeds of V. villosa with liquid-solid ratio

pH

microwave temperature and time as factors.The content of polysaccharides was determined by phenol sulfuric acid method

antioxidant activity of polysaccharides from seeds of V. villosa was detected by Fention reaction. Result: Optimum extraction conditions for polysaccharides from seeds of V. villosa were as followings:microwave extraction temperature 50℃

microwave treatment time 5 min

solid-liquid ratio 1:25 with pH 7;Under these conditions

extraction amount of polysaccharides was 30.043 mg·g-1.Antioxidant activity test showed that polysaccharides from seeds of V. villosa had strong antioxidant activity. Conclusion: This optimized technology was stable and feasible

it could provide experimental basis for comprehensive utilization and development of seeds of V. villosa.