Objective: To study the influence of Danhong injection on cerebrovascular hemodynamic parameters and nerve function related factors in patients with transient ischemic attack. Method: Fifty-eight patients with transient ischemic attack in our hospital were selected and randomly divided into control group and observation group with 29 cases in each group

the control group were treated with routine treatment

the observation group were treated with Danhong injection 40 mL+5% glucose solution iv

daily

for 2 weeks

based on the treatment of control group. Then cerebrovascular hemodynamic parameters and serum neuron specific enolase(NSE)

S100B protein (S-100B)

myelin basic protein (MBP)

glial fibrillary acidic protein (GFAP) of two groups before and after the treatment after 1 and 2 weeks were compared. Result: The mean flow velocity(Vmean)

maximum-portal flow velocity(Vmax)

minimum flow velocity (Vmin) and mean blood flow(Qmean) of observation group after the treatment for 1 and 2 weeks were higher than those in control group

resistance (R) were lower than that of control group

serum NSE

S-100B

MBP and GFAP were all lower than those of control group (all P<0.05). Conclusion: The influence of Danhong injection on cerebrovascular hemodynamic parameters and nerve function related factors in patients with transient ischemic attack is significant

and the injection can effectively improve the blood supply in brain.