Objective: The aim of this paper is to estimate the anti-bacterial effects of baicalin and borneol on Staphylococcus epidermidis. Method: A modified turbidimetry

which referred to the solution absorbance assay at 600 nm

was applied to determine the inhibition ratio of S. epidermidis growth by adding different concentrations of baicalin

borneol and baicalin-borneol mixed solutions. Result: The inhibition ratios of S.epidermidis growth of different baicalin concentration solutions with borneol added showed significant increase compared with blank baicalin solutions. The inhibition ratios were 49.78% with 1 200 mg·L-1 baicalin solution

and 13.41% with 600 mg·L-1 borneol solution

separately. The significant inhibition ratio which indicated the synergistic effect was 78.15% under the mixed solution with the baicalin concentration of 1200 mg·L-1 and borneol 600 mg·L-1. Conclusion: The compatibility of a certain amount of baicalin and borneol

which significantly enhanced the anti-bacterial effects of two compounds separately

indicated the outstanding synergistic effect on the inhibition of S.epidermidis growth.