Objective: Through studying the cumulative change process of main alkaloids from Coptis chinensis in Lichuan at different growth stages

provides scientific truth for standardization planting. Method: The effective components of C. chinensis were measured by UV spectrophotometry and HPLC methods. Result: The leafs and dry weight of root of C. chinensis were constantly increasing by the growth of the age growth. The main alkaloids content in different parts of C. chinensis was in the order of root>fibrous root>leaf. C. chinensis was growing fastest during two to three years stages

and the content of the tyrosine

total alkaloids

epiberberine

coptisine

palmatine and berberine was growing fastest too. These four alkaloids content was in the order of epiberberine>coptisine>palmatine>berberine. The proportion was insearsing that the sum content of the four alkaloids accounts for total alkaloids content. Conclusion: The result can be used to provide reference for planting and managing C. chinensis.