Objective: To study anti-fatigue effects of Xinjiang jujube juice and investigate its primary mechanisms. Method: One hundred and twenty male Kunming mice were randomly divided into four groups: the normal control group

Xinjiang jujube-juice low

middle

high dose group. The normal control group was fed with distilled water

while the experimental Xinjiang jujube -juice-feed group was fed with different concentrations (25%

50%

100%) at dose of 20 mL·kg-1for 30 days. After 30 days

each group mice were trained by doing a weight-loaded swimming until they were exhausted

and weight-loaded swimming time

serum lactates (LAC)

and serum urea nitrogen (BUN) and liver glycogen contents were measured after weight-loaded swimming. Result: Weight-loaded swimming times in all three doses of Xinjiang jujube juice groups were prolonged significantly

LAC and BUN levels in serum were decreased significantly

and liver glycogen content was increased significantly by comparing with normal control group(P<0.05). Conclusion: Xinjiang jujube juice has anti-fatigue effect.