CHEN Zhi-gang, LU Hong-da. Clinical Research of Combining Traditional Chinese Medicine with Western Medicine to Treat Non-small Cell Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(11): 322-324.
CHEN Zhi-gang, LU Hong-da. Clinical Research of Combining Traditional Chinese Medicine with Western Medicine to Treat Non-small Cell Lung Cancer[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(11): 322-324. DOI: 10.11653/syfj2013110322.
Objective: Discussion on combination of traditional Chinese and Western medicine in treatment of patients with non-small cell lung cancer(NSCLC)treatment. Method: Choose sixty-six patients with non-small cell lung cancer (Ⅲ
Ⅳperiod) who were received and cured in our hospital from June 2009 to June 2012
these patients were intravenous dropped docetaxel 75 mg·m-2 and cisplatin 25 mg·m-2
the former was d1 and the latter was d1-3
before using hexadecadrol 6 h and 12 h
the patients could respectively take orally dexamethasone 8 mg
former 0.5 h and were intramuscular injection diphenhydramine 40 mg
static injection cimetidine 300 mg. Giving stop vomiting drugs when they were proceeding to conventional chemotherapy
54 cases regarded as control group and were treated in this way.52 cases in the treatment were treated with 50 milliliter Eddie based on control group and joined 10% glucose solution to intravenous drop
one treatment every day. Two groups were continuously treated for 12 weeks. Observe and compare the efficacy of two groups
average rates of disease progression time and improved quality of life and reduce rates. Result: Total effective rate of 48.1% per cent of the control group
the study group total effective rate in the treatment of 64.8%
compared to the two groups
the difference statistically significant (P<0.05); control group and the study group's average time of disease progression respectively 128.35
174.56 d
compared to the two groups
the difference statistically significant (P<0.05); compared of two groups improved quality of life and reduce rates efficacy
control group karnofsky(KPS) score increase 10 (19.2%)
stable 13 cases (25%)
reduced in 29 cases (55.8%)
research group KPS scores improve to 18 cases (33.3%)
stable in 13 cases (24.1%)
reduced 23 cases (42.6%)
compared of two groups improved quality of life and reduce rates efficacy
the difference statistically significant (P<0.05). Conclusion: Effect treated with combination of traditional Chinese and Western medicine in the treatment of non-small cell lung cancer significantly
living longer
disease progression time for longer
play a role in improving the quality of life for patients with that merits promotion.