CHEN Ling-ling, ZHU De-quan, CAI Yue-e, et al. Optimization of Ultrasonic Extraction Technology of Caffeic Acid and Rosmarinic Acid from by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(12): 12-14.
CHEN Ling-ling, ZHU De-quan, CAI Yue-e, et al. Optimization of Ultrasonic Extraction Technology of Caffeic Acid and Rosmarinic Acid from by Orthogonal Test[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(12): 12-14. DOI: 10.11653/syfj2013120012.
Objective: To optimize ultrasonic extraction technology of caffeic acid and rosmarinic acid from Isodon lophanthoides. Method: A HPLC method was established to determine the content of caffeic acid and rosmarinic acid in I. lophanthoides.With yield of caffeic acid and rosmarinic acid as indexes
based on single factor test
extraction technology was optimized by L9(34) orthogonal test by screening extraction solvent
material-liquid radio
extraction time as factors. Result: Optimal ultrasonic extraction conditions were as follows:extracted 40 min with 20 times the amount of 30% ethanol. Conclusion: This optimized extraction technology was simple and economical with high extraction rate
it could provide a reference for development and utilization of I. lophanthoides.