Objective: To explore the clinical curative effect of traditional Chinese and western medicine combination for the treatment of advanced colorectal cancer. Method: Choose 63 cases of the patients with advanced colorectal cancer from January 2010 to 2012 June in our hospital. According to the random sampling method

divided into the control group witn 31 cases and research group with 32 cases. Control group given FOLFOX6 chemotherapy treatments

the rearch group on the basis of the control group treatment

combination with traditional Chinese medicine treatment

after two treatments

compared of the treatment effect of two groups

pain score numerical rating scale (NRS)

the life quality score FACT

and the patients serum carcinoembryonic antigen(CEA) and sugar chain antigen 19-9(CA199) change before and after treatment. Result: Compared with curative effect (64.5%)

the team curative effect (84.3%) increased significantly(P<0.05). After the treatment of the two groups

the pain score NRS decline

the life quality score FACT increase(P<0.05).After the treatment

the two groups of patients serum CEA and CA199 were significantly decreased

significant difference

there is statistical significance (P<0.05). After the treatment

compared to the control group patients serum CEA and CA199 comparison

the rearch group obviously improved(P<0.05). Conclusion: Combine traditional Chinese and western medicine combination for the treatment of advanced colorectal cancer operation the effect is obvious and it is worth clinical promotion.