Objective:To establish a quality standard of Shegan Dilong Granules for scientific evaluation and effective control of its quality to provide a reliable basis. Method: TLC was used for identifying the herbs in the formula and the content determination of irisflorentin by HPLC was also revised. Result: The method was established to distinguish Belamcanda sinensis

pberetima

rhizome Menispermi and Schisandra chinensis. The spots in the TLC were clear

and with no interference from negative control. The HPLC separation was performed on C18 column

the mixture of acetonitrile-0.2% phosphoric acid water was used as mobile phase. The detection wavelength was set at 266 nm

irisflorentin was linear in the range of 0.342 2-86.60 mg·L-1;regression equation was A＝51 639C＋7 222 (R2＝0.999 5

n=10);the average recovery was 99.8%

RSD 1.50%. Conclusion: The method was simple and accurate with a good reproducibility

and can be used for the control of Shegan Dilong Granules.