Objective:To establish qualitative control standard of Baikejing syrup. Method: TLC was used for qualitative analysis of Scutellaria baicalensis

Phellodendron chinense

Citrus reticulata

Ephedra sinica

the content of baicalin was determined by HPLC. Result: Baikejing syrup for samples and reference substances showed the same color dot in corresponding chromatograph position;Sinochrom ODS bp C18 column (4.6 mm×250 mm

5 μm) and ODS pre-column were adopted with mobile phase of methanol-water-phosphoric acid(45∶55∶0.04)

detection wavelength was at 315 nm

baicalin showed a good linear relationship within the range of 0.08-0.4 μg(r=0.999 8)

the average recovery was 100.9% with RSD of 1.7%. Conclusion: This method was sensitive

reproducible and reliable

it could be used for quality control of Baikejing syrup.