Objective:To study the protection and treatment effects of Buqing granules on galactose cataract. Method: Animal model of galactose cataract was induced in SD rats.The rats were divided into six groups:black control group

model group treated by daily intraperitoneal injection of 50% D-galactose solution (10 g·kg-1) for 15 days

positive control group treated by Zhangyan uspension 0.02 g·kg-1 everyday

high

medium and low dose groups of Buqing granules (0.8

0.4

0.2 g·kg-1). Recorded the lens turbidity was recorded before and after modeling from the first day to 3

7

14.At the end of the experiment

superoxide dismutase (SOD) and malondialdehyde (MDA) was detected. Result: The lens in control group was transparent

in model group lens opacities occurred at the third day

in the three dose groups of Buqing granules occurring time and extent of lens opacities at 3

7 and 14 days were significantly lower than the model group(P<0.05). SOD activity was significantly higher than the model group(P<0.05)

MDA was significantly lower than that in the model group (P<0.05). Conclusion: The Buqing granules had better prevention and treatment in rats with galactose cataracts.