芪参益气滴丸对慢性心力衰竭患者心功能及血浆超敏C反应蛋白和B型脑钠肽的影响

吴波; 袁文金

doi:10.11653/syfj2013130308

您当前的位置：

首页 >

文章列表页 >

芪参益气滴丸对慢性心力衰竭患者心功能及血浆超敏C反应蛋白和B型脑钠肽的影响

更新时间：2024-01-04

- 芪参益气滴丸对慢性心力衰竭患者心功能及血浆超敏C反应蛋白和B型脑钠肽的影响
- Effect of Qishen Yiqi Dripping Pills on Heart Function and High-sensitivity C-reactive Protein and B-type Brain Natriuretic Peptide Lvels in Patients with Chronic Heart Failure
- 中国实验方剂学杂志 2013年19卷第13期页码：308-311
- 作者机构：
- 作者简介：
- 基金信息：
- DOI：10.11653/syfj2013130308
  中图分类号：
- 纸质出版日期：2013
- 稿件说明：
移动端阅览
吴波, 袁文金. 芪参益气滴丸对慢性心力衰竭患者心功能及血浆超敏C反应蛋白和B型脑钠肽的影响[J]. 中国实验方剂学杂志, 2013,19(13):308-311.

WU Bo, YUAN Wen-jin. Effect of Qishen Yiqi Dripping Pills on Heart Function and High-sensitivity C-reactive Protein and B-type Brain Natriuretic Peptide Lvels in Patients with Chronic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(13): 308-311.
吴波, 袁文金. 芪参益气滴丸对慢性心力衰竭患者心功能及血浆超敏C反应蛋白和B型脑钠肽的影响[J]. 中国实验方剂学杂志, 2013,19(13):308-311. DOI： 10.11653/syfj2013130308.

WU Bo, YUAN Wen-jin. Effect of Qishen Yiqi Dripping Pills on Heart Function and High-sensitivity C-reactive Protein and B-type Brain Natriuretic Peptide Lvels in Patients with Chronic Heart Failure[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(13): 308-311. DOI： 10.11653/syfj2013130308.

摘要

目的: 探讨芪参益气滴丸对慢性心力衰竭(CHF)患者心功能及血浆超敏C反应蛋(hs-CRP)和B型脑钠肽(BNP)的影响。方法: 120例患者随机分为治疗组和对照组

均给予抗心力衰竭常规治疗

治疗组在常规治疗基础上加用芪参益气滴丸

疗程12周。治疗前后用彩色多普勒测定心功能指标左室射血分数(LVEF)、左室收缩末期内径(LVESD)、左室舒张末期内径(LVEDD);测定血浆hs-CRP和BNP水平。结果: 两组患者治疗12周后临床疗效比较

差异有统计学意义(P<0.05);两组治疗后心功能指标LVEF

LVESD

LVEDD水平比较

差异均有统计学意义(P<0.01);两组治疗后hs-CRP

BNP水平比较

差异均有统计学意义(P<0.01)。结论: CHF患者在常规治疗基础上加用芪参益气滴丸治疗

可明显降低血浆hs-CRP及BNP水平

同时降低LVESVI

LVEDVI

增加LVEF

改善心功能。

Abstract

Objective:To investigate the effect of Qishen Yiqi dripping pills on heart function and high-sensitivity C-reactive protein(hs-CRP)and B-type brain natriuretic peptide (BNP) levels in the patients with chronic heart failure. Method: One hundred and twenty CHF patients were divided into routine therapy group and Qishen Yiqi dripping pills group.Left ventricular ejection fraction(LVEF)

left ventriculay end systolic diameter(LVESD)and left ventrieular end diastolic diameter (LVEDD) before and after treatment were detected.Serum hs-CRP and BNP were measured by rapid fluorescence immunoassay. Result: LVEDD and LVESD were shortened

LVEF was improved in Qishen Yiqi dripping pills group(P<0.05).Concentrations of serum hs-CRP and BNP levels were decreased in Qishen Yiqi dripping pills group after treatment(P<0.01). Conclusion: The heart function is further improved

concentrations of serum hs-CRP and BNP levels are further decreased by treated with Qisben Yiqi dripping pills in heart failure patients.

关键词

Keywords

references

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

基于中西医病证结合特点的慢性心力衰竭动物模型分析

升陷汤对慢性心力衰竭大鼠心肌微血管损伤的保护作用

慢性心力衰竭气虚血瘀证预测模型的构建与验证

益气温阳活血利水组分配伍对CHF大鼠心功能及心肌能量代谢的影响

基于“虚气留滞”探讨铁死亡对慢性心力衰竭的调控机制及中医药防治进展