Objective: To establish a method for determining the content of sodium in extract of Salvia miltiorrhiza. Method: With nitric acid as digestion system

extract of S. miltiorrhiza was digested by microwave

the content of sodium belonging to this extract was determined by inductively coupled plasma mass spectrometry(ICP-MS).In order to correction response signal changes and eliminate influence of matrix effect and instrument drift

chromium was selected as an internal standard solution. Result: Linear range of sodium was 0.00-10.00 mg·L-1(r=0.999 9)

with poplar leaves as work standards

average recovery was determined as 90.4% (RSD 3.8%

n=6). Conclusion: This method had good stability

reproducibility and precision

it could be used to determining the content of sodium in extract of S. miltiorrhiza.