Objective: To observe the effect on treating diabetic foot with tetramethylpyrazine(TMP) combined with foot bath. Method: Ninty patients were randomly divided into A(control group)

B(TMP treated group)

C(TMP combined with foot bath treated group)

30 cases in each group were given conventional treatment. On this basis

group B was treated with TMP. On the basis of the group B

group C was treated with traditional Chinese medicine foot bath accordance with the principles of the syndrome differentiation. 4 weeks later. Effect of the treatment of patients

the improvement of nerve conduction velocity (MCV) and sensory nerve conduction velocity (SCV) in each group were compared. Result: compared with group A

the treatment of patients with total efficiency in groupB and C were significantly improved and the difference was statistically significant (P<0.05). The treatment of patients with total efficiency in group C was significantly improved than that of in group B

and the difference was statistically significant (P<0.05); compared with group A

the SCV in groupB and C were significantly improved and the difference was statistically significant (P<0.05)

The SCV in group C was significantly improved than that of in group

and the difference was statistically significant (P<0.05). Conclusion: On the basis of conventional Western medicine treatment

TMP combined traditional Chinese medicine foot bath treatment of diabetic foot can significantly improve the treatment efficiency and SCV

which can Promote lesion recovery of neurological function

and it is worthy of clinical application.