Objective: To optimize extraction technology of Peitu Qingxin granules. Method: With yield of volatile oil as index

single factor tests were adopted to investigate effect of the amount of water

soaking time and distillation time on extraction technology of volatile oil.With yield of phillyrin and extract rate as comprehensive evaluation index

based on single factor tests

effect of extraction time

the amount of water

extraction times and soaking time on water extraction technology was investigated by orthogonal test. Result: Optimum extraction technology of volatile oil was as following:soaked 0.5 h with 8 times the amount of water

then distilled 6 h.Optimum water extraction technology conditions were as follows:boiled 3 times with 10 times the amount of water

1 each time. Conclusion: Optimized extraction technology was simple

stable and feasible

it could settle foundation for molding technology of Peitu Qingxin granules.