Objective: To observe clinical efficacy of diarrheaⅠrecipe for treatment of pediatric rotavirus (HRV) diarrhea. Method: Sixscore patients which had damp-heat rotavirus diarrhea were randomly divided into control group and the observation group

60 cases in each. Two groups were given necessary symptomatic treatment

fluid therapy and oral montmorillonite powder. The control group oral ribavirin particles

the treatment group oral diarrheaⅠrecipe. Course of treatment was 3 d. Diarrhea

vomiting and fever's disappearance time were recorded. The score of damp-heat syndrome were assessed before and after treatment

rotavirus was detected and myocardial enzymes observed. Result: The total effective rate of the treatment group was 96.67%

whicn was higher than the control group's (78.33%

P<0.05). The average disappearance time of diarrhea

vomiting

fever in observation group were significantly shorter than that in the control group (P<0.01). The HRV negative conversion rate in observation group was dramaticlly incerased compared with the control group (90.0% vs 73.33%

P<0.01). The score of damp-heat syndrome in observation group (4.5±1.7)

was lower than that in control group (6.1±1.8) (P<0.01). The level of creatine kinase (CK) and creatine kinase isoenzyme (CK-MB) in observation group was lower than the control group (P<0.05

P<0.01). Conclusion: DiarrheaⅠrecipe can shorten the course

reduce symptoms

improve clinical outcomes of the pediatric rotavirus diarrhea

also it can clear the HRV

and reduce myocardial injury.