Exploration of Drug Treatment Law for Ulcerative Colitis Based on Text Mining Technology[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(15): 329-332.
Exploration of Drug Treatment Law for Ulcerative Colitis Based on Text Mining Technology[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(15): 329-332. DOI: 10.11653/syfj2013150329.
Objective: To explore treatment law of ulcerative colitis with traditional Chinese medicine and western medicine. Method: Taking data mining technology
combined with visualization
literarure data for treating ulcerative colitis were collected in Chinese biomedical literature database.Data slicing algorithm based on sensitive keywords frequency statistics was adopted
combined with literature review and artificial reading noise reduction
then treatment law of traditional Chinese medicine and western medicine for ulcerative colitis was investigated.Law showed of one-dimensional and two-dimensional network diagram. Result: Using frequency of western drugs for treatment of ulcerative colitis was in order of sulfasalazine>metronidazole>dexamethasone>prednisone>hydrocortisone
dexamethasone was commonly associated with other western medicine;Using frequency of Chinese patent drugs was in order of Yunnan Baiyao>Wumei pills>Bupi Yichang pills>Lizhong pills>mirabilitum praeparatum
Buzhong Yiqi pills and Bupi Yichang pills was always associated with other Chinese patent drugs;Chinese materia medica was in order of Rhizoma Coptidis>Rhizoma Atractylodis Macrocephalea>Radix Pulsatillae>Radix Astragali>Fructus Mume
Rhizoma Coptidis
Rhizoma Atractylodis Macrocephalea and Radix Astragali often combined with other herbs;Bupi Yichang pills
Yunnan Baiyao and Wumei pills were always associated with dexamethasone
metronidazole and sulfasalazine. Conclusion: Text mining technology could be adopted for objective summing up treatment law of traditional Chinese medicine and western medicine for ulcerative colitis
then provide useful exploration and reference to clinical experience.