Objective: To discuss the application of mathematical modeling strategies in material foundation of traditional Chinese medicine(TCM)

and try to establish a set of objective modeling methods. Method: From the database establishment

data preprocessing

modeling strategy choosing and model's evaluations the most appropriate recognition model for CHMP-markers was choose. Result: Seventeen kind of modeling strategies from 64 was selected

and 4 kind was chosen in view of the visual expression ability

and PLS was selected as the most appropriate one via statistical simulation. Conclusion: It is difficult to find ready-made formula or law express the relation between the relation of Chinese medicine medicinal properties and material base

exhaustive method can be used to choose the most suitable model

database establishment

data preprocessing

modeling strategy choosing and model's evaluations are the 4 key steps.