Objective: To study the efficacy and safety of Mongolian SA dew de Di+Xieri GA-4 soup in the treatment of early diabetic nephropathy (Rexingxijin disease). Method: According to digital method

80 patients with divided into two groups randomly treatment group and control group

40 cases each. Treatment group on the basis of conventional treatment with western medicine fall blood sugar added with Mongolian SA dew de Di+Xieri GA-4 soup treatment. Control group with western medicine fall blood sugar

a course of 8 weeks. Observed two groups' Mongolian medicine symptoms

24 h urine trace albumin before and after the treatment. Result: The clinical total effective rate of treatment group was 90%

was better than that of control group 77.5% (P<0.05); After treatment

24 h urine trace albumin excretion rate(49.45±16.86)μg·min-1 of treatment group was lower than control group(96.52±22.56)μg·min-1(P<0.01). Treatment group in Mongolian medicine single symptom urine was cloudy

frequency quantity more fatigued

lumbar debility improvement better than that in control group (P<0.05). Two groups during treatment without any adverse reaction occurred. Conclusion: Mongolian SA dew de Di+Xieri GA-4 soup in the treatment of early diabetic nephropathy is safe and effective

worthy of clinical use and further study.