Objective: To optimize clarification technology of Shenyu oral liquid. Method: Effects of KBT-ZTC flocculation

enzymatic

microfiltration

enzymatic-microfiltration and flocculation-microfiltration on quality of Shenyu oral liquid were investigated with the contents of ginsenoside and total polysaccharides

clarity and stability as evaluation indexes. Result: Optimum clarification method was flocculation-microfiltration which could improve retention rate of effective ingredients of Shenyu oral liquid and make this oral liquid clear and stable.The contents of ginsenoside Re

Rg1

Rb1 were 0.331 1

0.282 8

0.098 4 mg·g-1 and the content of total polysaccharides was 96.33 mg·g-1. Conclusion: Impurities could removed effectively and effective ingredients were retained by KBT-ZTC flocculation-microfiltration method

this process was stable and could be used as clarification technology of Shenyu oral liquid.