Objective: To establish HPLC fingerprint for different processed products of Arecae Semen. Method: HPLC was adopted

Chromatographic conditions were performed on Agilent TC-C18 column(4.6 mm×250 mm

5 μm)

acetonitrile-water as mobile phases in gradient elution

detection wavelength of 283 nm and column temperature at 30℃

flow rate of 1.0 mL·min-1.HPLC fingerprint for different processed products of Arecae Semen was established. Result: RSD of methodological study in HPLC fingerprint were less than 1.5%

which was in line with relevant regulations.There were 10 common peaks in fingerprint of 10 batches of samples

we found three new ingredients in frying process

these three new ingredients increased gradually

reached peak value of Arecae Semen Tostum

then reduced gradually;But other ingredients decreased gradually in frying process. Conclusion: Change of fingerprint could reveal that materials basis of Arecae Semen has been changed at a certain degree

which provided a reference for processing principle of Arecae Semen.