Objective: To explore TCM syndromes in abnormalglucose metabolism metabolic syndrome(MS) rats based on syndrome detecting from recipe used. Method: After the establishment of the MS rat model

according to blood sugar level

rats were randomly divided into MS group

group A

group B

group C

group D. Chaihu Tang

Huanglian Wendan Tang

Zhibai Dihuang Wan and Xuefu Zhuyu Tang were given. At week 12 and 15 the weight

blood pressure

fasting blood glucose(FBG)

triglycerides(TG)

high density lipoprotein(HDL-C) and insulin levels were measured. Result: Compared with the model group

in A

B

C

D group

body weight

blood pressureand FBG had no significant difference

in A

B and D groups TG level significantly decreased

and in B group HDL-C was significantly increased (P<0.05)

in A and D group fasting insulin(FINS) and homeostasis model assessment insulin resistance(HOMA-IR) were significantly lowered (P<0.01). Conclusion: Abnormal glucose metabolism MS rats may exist hepatogastric stagnant heat

phlegm each node certificate

Yin Heat Syndrome and blood stasis syndrome

and the four syndromes indicated mixed signs.