Objective: To explore the clinical efficacy of Chinese medicine combined with pamidronate disodium on cancer pain in the bone metastatic in patients. Method: Sixty patients were randomly divided into two groups

treatment group with 30 cases and control group with 30 cases. The control group was given pamidronate disodium

the treatment group was given Chinese medicine and pamidronate disodium. Result: The total effective rate in the treatment group was 80%

and was 40% in the control group. The difference was statistically significant (P<0.01). For the analgesic effect

in the treatment group relief rate was 83.3%

which was higher than that in the control group (46.70%)

the difference was statistically significant (P<0.05). Conclusion: The Chinese medicine combined with pamidronate disodium in treatment of metastatic bone cancer is better than single pamidronate disodium

which can improve the patients quality of life in clinical application.