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纸质出版日期:2013
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左振魁, 席作武, 韩佳瑞, 等. 解毒化瘀方治疗肛瘘术后患者60例[J]. 中国实验方剂学杂志, 2013,19(18):326-329.
ZUO Zhen-kui, XI Zuo-wu, HAN Jia-rui, et al. After Jiedu Huayu Decoction Treated 60 Patients with Postoperative Archosyrinx’s Clinical Research[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(18): 326-329.
左振魁, 席作武, 韩佳瑞, 等. 解毒化瘀方治疗肛瘘术后患者60例[J]. 中国实验方剂学杂志, 2013,19(18):326-329. DOI: 10.11653/syfj2013180326.
ZUO Zhen-kui, XI Zuo-wu, HAN Jia-rui, et al. After Jiedu Huayu Decoction Treated 60 Patients with Postoperative Archosyrinx’s Clinical Research[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(18): 326-329. DOI: 10.11653/syfj2013180326.
目的: 观察解毒化瘀方内服、熏洗对肛瘘术后患者创面恢复的影响。方法: 120例低位肛瘘术后患者随机按数字法分为对照组和观察组各60例。两组患者在行肛瘘切除术后常规使用抗生素治疗5 d
创面采用生肌玉红膏涂于纱布条外敷无菌纱块包扎固定。观察组加用解毒化瘀方内服和熏洗
疗程14 d。记录术后疼痛、肿胀、渗出评分
记录创面愈合天数、便血天数、脓腐脱落天数、创面疤痕面积
进行肛门功能评价
检测成纤维细胞生长因子(bFGF)。结果: 观察组总有效98.33%优于对照组的85.0%(P<0.05);治疗后1
3
7
14 d观察组疼痛、肿胀、渗出评分均低于对照组(P<0.05
P<0.01);观察组创面愈合天数、便血天数、脓腐脱落天数均少于对照组
创面疤痕面积小于对照组(P<0.01);对照组治疗后干便、稀便、气体、需要衬垫、生活方式改变评分及总分均明显上升(P<0.01)
观察组上述指标与治疗前相比变化不明显;观察组血清bFGF高于对照组(P<0.01)。结论: 解毒化瘀方内服、熏洗能明显减轻肛瘘术后疼痛、水肿、渗液、出血等症状
促进创面修复、愈合
且不影响肛门直肠功能
是治疗肛瘘术后的有效方剂
值得临床使用
Objective: Observed the effect of wound healing using Jiedu Huayu decoction oral and fumigation to the patients who had postoperative archosyrinx. Method: The 120 patients with low anal fistula after postoperative treatment were randomly divided into control group and observation group. Each had 60 cases. The two groups of patients after did anal fistulectomy
used of antibiotics treatment 5 d. Wounds were treated with the Shengji Yugao of gauze applied externally and sterile gauze bandaged. The observation group was treated with Jiedu Huayu decoction oral and fumigation. Treatment for 14 d. Recorded postoperative pain
swelling
exudation scores. Recorded wound healing days
the hematochezia days
pus rot off days
the wound scars area
and anus function evaluation
the detection of fibroblast growth factor (bFGF). Result: The total effective 98.33% was better than the control group 85.0% (P<0.05); 1
3
7
14 d observation group after treatment
pain
swelling
exudation scores were lower than the control group (P<0.05
P<0.01);observation group wound healing days
the hematochezia days
pus rot off days were less than the control group
wound scar area was less than the control group (P<0.01); dry stools
loose stools
gas
need gasket
lifestyle change score and total score were significantly increased (P<0.01). The observation group did not change significantly compared to the indicators before treatment. The observation group serum bFGF was higher than control group (P<0.01). Conclusion: Jiedu Huayu decoction oral and fumigation could significantly reduce the anal fistula postoperative pain
edema
exudate
bleeding and other symptoms. Promoted wound healing and did not affect the anal anorectal function. It was an effective prescription for the treatment of anal fistula
worthy of efficacy use.
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