Objective: To determine the concentration of trace elements

so as to provide information for the qualitative control of Cordyceps sinensis fermented mycelium

which is more strictly than the standard of Chinese Pharmacopoeia. Method: Flame atomic absorption technique was applied to analyze the content of zinc

iron

manganese

copper and plumbum from fermented mycelium of Cordyceps sinensis respectively. Result: The content of trace elements was listed here in order of relative quantity

Fe>Mn>Zn>Cu>Pb. All calibration curves showed good linearity (r>0.9994). The RSD of reproducibility was between 0.54% and 0.86%. The average recoveries were between 96.05%-101.71%. The RSD of recovery was between 0.32% and 1.91%. Conclusion: The method is simple with good precision and sensitivity and the result was reliable. The content of trace elements in fermented mycelium of C. sinensis is according to the requirement given by the WHO.