Objective: To establish quality standardS of Pingxiao granules. Method: Ephedrae Herba

Paeoniae Radix Alba and Cnidii Fructus in Pingxiao granules were identified by TLC;The content of ephedrine hydrochlorid was determined by RP-HPLC

chromatographic conditions were as follows:Hedera ODS2 column(4.6 mm×200 mm

5 μm)

mobile phase of acetonitrile-0.1% phosphoric acid(3:97)

flow rate of 1.0 mL·min-1

detection wavelength 207 nm

column temperature at 30℃. Result: Spots of Ephedrae Herba

Paeoniae Radix Alba and Cnidii Fructus in Pingxiao granules on TLC could be well separated.Ephedrine hydrochlorid showed a good linear relationship at the range of 0.069 6-0.417 6 μg (r=0.999 0)

the average recovery was 99.35% with RSD 1.84%

the contents of ephedrine hydrochlorid in three batches of Pingxiao granules were 0.202 2

0.209

0.207 2 mg·g-1

respectively;Temporarily intended the content of ephedrine hydrochlorid should more than 0.17 mg per 1 g of this product. Conclusion: This established method was simple

specific

sensitive and reproducible

it was suitable for quality control of Pingxiao granules.