Objective: Discuss the clinical efficacy of Tongfu Runzao decoction of oral antidiabetic drugs in poorly controlled gastrointestinal-heat type 2 diabetes(T2 DM). Method: Divide the 120 cases of oral hypoglycemic drugs poorly controlled type gastrointestinal excess heat T2 DM into control group and observation group randomly

each group has 60 cases. Both groups were treated with recombinant insulin glargine

observation group took Relaxing moistening party additionally

therapy for eight weeks.Monitor fasting blood glucose after treatment.2 h postprandial blood glucose(2 hPG);test glycosylated hemoglobin before and after treatment

fasting insulin (FINS) and blood lipids;record the time of blood glucose

record usage of recombinant insulin glargine per week

record hypoglycemia occurred and gastrointestinal excess heat syndrome score. Result: The 2 hPG

HbA1c and FINS of the observation group is lower than the control group (P<0.05). The ISI of two groups both increased

while the significant increasing occurred in the observation group (P<0.01). Compared to the control group

the improvements of weight and waist circumference were all more obvious (P<0.05). During the 4

6

8 weeks after the treatment

the dose of recombinant insulin glargine of the observation group was all inferior to that of the control group (P<0.01). The average time (14.2±2.48) d of recovering blood glucose of the observation group was less than the time (17.8±2.79) d of the control group (P<0.01). The incidence of hypoglycemia and average people-time were both lower than the control group (P<0.01). Besides

after the treatment

the TG

TC and LDL-C level were lower than the control group excepting the HDL-C level higher than that of control group (P<0.05). The scores of the main symptoms (such as thirsty

like of cold drinks

distention and fullness and stool induration) were lower than control group (P<0.01). Conclusion: The Tongfu Runzao decoction can reduce the 2 hPG

HbA1c in the T2 DM

which could be controlled well by oral antidiabetic drugs

prompting the blood glucose of patients reaching the standard level. It can also decrease the usage of insulin

reducing the incidence of hypoglycemia caused by insulin. Can effectively improve the clinical symptoms

improve patient quality of life.