Objective: To observe the clinical efficacy for the treatment of mycoplasma pneumoniae pneumonia children with phlegm-heat closed lungs by Qingfei Tongluo method. Method: Sixty patients were randomly divided into the treatment group and the control group

the two groups of patients were treated with intravenous infusion of azithromycin therapy for five days

and intravenous infusion of kitasamycin therapy for two days

treatment group were added to Qingfei Tongluo agent orally 7 days. Comprehensive efficacy and the total score of the clinical signs and symptoms before and after treatment were compared between the two group to evaluat the clinical efficacy Qingfei Tongluo method. Result: In the treatment group

18 cases were cured

9 cases were markedly effective

the total effective rate was 96.67%.In the control group cured 10 cases were cured

8 cases were markedly effective

the total effective rate was 93.33%;Upon examination

the difference between the two groups was significant (P<0.05). The clinical signs and symptoms total score before and after treatment in the treatment group was significantly better than the control group (P<0.05). Conclusion: Treatment of children Mycoplasma pneumoniae pneumonia with phlegm-heat closed lungs by Qingfei Tongluo method has significant effect and important clinical value to further study.