DENG Di, WENG Zi-cong, HUANG Yu-yin, et al. Preparation of Olive Chewable Tablets and Investigation of Its Scavenging DPPH Free Radicals[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 24-27.
DENG Di, WENG Zi-cong, HUANG Yu-yin, et al. Preparation of Olive Chewable Tablets and Investigation of Its Scavenging DPPH Free Radicals[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 24-27. DOI: 10.11653/syfj2013210024.
Objective: To prepare olive chewable tablets and investigate its antioxidant capacity. Method: With flavor
appearance
taste and hardness as composite index
orthogonal test was adopted to optimized formulation technology of olive chewable tablets by taking dosage of lactose
magnesium stearate
mannitol and PVP-k30 as factors.The content of polyphenols from olive chewable tablets was determined by HPLC
chromatographic conditions were:C18 column(4.6 mm×250 mm
5 μm)
mobile phase of acetonitrile-0.085% phosphoric acid(8:92)
detection wavelength 280 nm
flow rate 1 mL·min-1.Antioxidant capacity of olive chewable tablets was evaluated by investigating its scavenging DPPH free radicals. Result: Optimal formulation technology was as following:33% raw material medicine
10% lactose
35% mannitol
10% PVP-K30
1% magnesium stearate
each tablet (0.38 g) containing gallic acid of 1.64 mg
ability of olive chewable tablets to scavenging DDPH free radicals was better than Vitamin C. Conclusion: These prepared olive chewable tablets had antioxidant health function with good taste
it could provide some certain ideas on protection and development of geoherbs in the South China.