Objective: To study the apoptosis-inducing effects of Weikang Shuning in human gastric cancer cells in vitro l. Method: The SGC-7901 cells were cultured in the Weikang Shuning liquid with the concentration is 200

400

800 mg·L-1for 48 and 72 hours

then the cells were collected and the flow cytometry was used to detect the change of mitochondria electric potential. ELISA method was used to detect the change of cytochrome(Cyt c). Prepare of cell slides

the immunocytochemistry method was used to study the effects of Weikang Shuning on the indexes of the induced SGC-7901 including Bcl-2 and Bax. Result: Weikang Shuning could decreased the membrane potential and release of Cyt c of gastric cancer cells (P<0.05). The expression of Bax was strengthened (P<0.05)

and the expression of Bcl-2 was lessened (P<0.05). Conclusion: The mechanism of promoting gastric cancer apoptosis by Weikang Shuning in vitro may be associated with the mitochondrial apoptotic pathway.