Objective: Observe the effects of Jiedu Quyu prescription combined with chemotherapy on expression of Bcl-2/Bax and apoptosis of MCF-7 cells. Method: Use the MTT to determinate the inhibitory action of medicine to MCF-7 cells; flow cytometry to detect the apoptotic index; immunocytochemistry to examine the Bcl-2

Bax expression. Result: Jiedu Quyu prescription can inhibit the MCF-7 cells proliferation

and on time

drug concentration-dependent; of chemotherapy synergies. Flow cytometry find that Jiedu Quyu prescription on inducing apoptosis in MCF-7 cells early advantage; and it also can decreasing the Bcl-2 expression in MCF-7 cells

also depend on time and drug concentration. Conclusion: The Jiedu Quyu prescription displayed its effect of inhibiting and inducing to apoptotic. It may be associated with the down-regulate of the expression of Bcl-2.