Objective: To study the effects of Tussah male moths oil on the content of testosterone

substance metabolism and anti-fatigue ability of rats. Method: By using the model of high-intensity endurance training

Wistar rats were divided into 5 groups

10 in each group control group (C group)

motion control group (T group)

exercise+ig low-dose Tussah male moths oil group (TML group)

exercise+ig middle-dose Tussah male moths oil group (TMM group)

and exercise+ig high-dose Tussah male moths oil group (TMH group). Administration was performed once a day. The rats in Tussah male moths oil groups were gavaged with 0.5

1

3 g·kg-1 with ig volume of 5 mL·kg-1. The rats in C and T groups were given same volume saline. After 42 days of exhaustive swimming training

body weight

swimming time and serum testosterone and other biochemical markers were measured. Result: The body weight of the rats in Tussah male moths oil groups was increased compared with T group (P<0.05)

and the swimming time was longer than T group (P<0.01). Serum corticosterone was lower than the T group (P<0.01). Changes in the ratio of serum testosterone/corticosteron were more consistent with testosterone changes among the groups. Liver glycogen (P<0.05)

muscle glycogen (P<0.01) and hemoglobin(P<0.01) in Tussah male moths oil group were higher than in T group

but the serum urea nitrogen was lower than the T group (P<0.01). Conclusion: Tussah male moths oil can alleviate the impact of high-intensity exercise on serum testosterone

and maintaine it at normal physiological levels;it can also promote protein synthesis

inhibit degradation of amino acid and protein

and increase hemoglobin and glycogen reserves in rats exercise training.