Exploring Association Rules of Syndrome and Herbal Medicine within Framework of Traditional Chinese Medicine on Coronary Heart Disease Through Text Mining Approach
YANG Jing, TIAN Jing-ping, TAN Yong, et al. Exploring Association Rules of Syndrome and Herbal Medicine within Framework of Traditional Chinese Medicine on Coronary Heart Disease Through Text Mining Approach[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 319-322.
YANG Jing, TIAN Jing-ping, TAN Yong, et al. Exploring Association Rules of Syndrome and Herbal Medicine within Framework of Traditional Chinese Medicine on Coronary Heart Disease Through Text Mining Approach[J]. Chinese journal of experimental traditional medical formulae, 2013, 19(21): 319-322. DOI: 10.11653/syfj2013210319.
Objective: Explore the principle of pattern-herbs of Chinese medicine on coronary heart disease (CHD)by text mining analysis. Method: Download the literatures about CHD from Chinese Bio-Medical Literature Database. Mine the rules of traditional Chinese medicine(TCM) pattern and Chinese herbal medicines by data slicing algorithm. The results are showed visually with Cytoscape 2.8 software. Result: The pattern of qi deficiency and blood stasis is the main TCM symptom. Heart blood stasis syndrome and deficiency of qi and yin are the common pattern. The center TCM herbs of CHD are Radix Salviae Miltiorrhizae
Radix Astragali
Radix Puerariae
Radix Ginseng
Flos Carthami
Rhizoma Chuanxiong
Radix Notoginseng
Radix Ophiopogonis. As is shown in directional mining
the center herbs for damp-heat pattern are similar with those treatments for CHD. Conclusion: Text mining approach provides an important method in exploring the rules of pattern-herbs of Chinese medicine.